The perennial and widespread herb Lythrum salicaria L., also called purple loosestrife, is a\nplant that is traditionally used in European medicine. Purple loosestrife is known for its ability to\ntreat internal disorders, such as gastrointestinal issues or hemorrhages. Our objective was to take\nanother look on this natural source of ellagitannins in terms of biological activities. Exploration of\nthe phytochemical content of an extract of aerial parts of Lythrum salicaria L. was completed before\ninitiating research on its biological effects towards keratinocytes, reconstructed epidermis, and skins.\nThe potential of the natural compounds were evaluated by topical treatment of reconstructed tissues.\nThe extract and one of its major compounds were able to act as pro-differentiating and protecting\nagents towards skin cells by stimulating the expressions of markers taking part in the structure\nof epidermis and dermis. Also, the extract showed beneficial effects on the global morphology of\nthe skin. Thus, Lythrum salicaria L. constitutes a new natural source for the development of active\ningredients for the dermo-cosmetic field.
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